Q & A: Would you recommend switching from atorvastatin to rosuvastatin?

Q & A: Would you recommend switching from atorvastatin to rosuvastatin?

October 31, 2019 7 By Jose Scott


RobT07: Hello Doc. If after a few
months on atorvastatin, if someone’s LDL dropped from 120 to 47,
would you still recommend switching to rosuvastatin? Great question, RobT07.
And the answer is yes, I would. And here’s why. We talked about pleiotropic
activities when we’re talking about K2. A pleiotropic activity is you give it for
one thing but it actually helps on something else. Here’s what happens with
statins. Mostly statins are given to lower LDL. But think about the logic, and
I know you’ve seen a lot of our videos. I’ve seen you’re around a good bit in
terms of your comments. Half the people that have a heart attack have a normal
LDL. So is it really LDL that’s causing this? Probably not. On the other hand,
there’s a big thing in terms of inflammation. I’m not gonna go down that
trail right now. But there’s a very smart guy named Paul Ridker at Harvard who
noticed this over a decade ago that whether people’s LDL was low or high,
quite often, if they’re on statins, they still had a significant decrease in
heart attack. And well, if they’re on statins, they had a significant heart
attack risk. He theorized that was due to inflammation, and that science
has been proven out multiple times. Why did I go down that path? Because here’s
the problem. People are still taking atorvastatin (Lipitor) watching their LDL
and thinking they’re getting a good impact. Lipitor is the least likely of
all of the statins to impact inflammation. It still does, but here’s
two things. If you’re a female, it’s less likely And if you have insulin
resistance, it’s less likely. Over half of us are have insulin resistance or
diabetes, and half of us are females. So and in the by far the biggest
prescription given in the statin areas is Lipitor. So from that perspective
I would say a huge portion statin prescriptions are doing more damage than they’re helping.