New HIV Vaccine! ‘Mosaico’

New HIV Vaccine! ‘Mosaico’

January 25, 2020 8 By Jose Scott


okay. Dukey look there. Look at that.
What’s that? Say ‘hi’ buddy. They’ve missed you. Can I have a kiss,
Bubba? Hey Give me a kiss. Thank you. Thank you, boy. What’s going on everybody? Raif Derrazi here. And today I want
to talk about a new HIV potential, HIV vaccine that is going into clinical
trials this fall 2020. Yet another way that we are working towards ending the
HIV epidemic. And so let’s dive right in. There was an article that was published
yesterday by the LA Times on the sixth. So I’m going to be basically summarizing
what this article and what the information from the clinical trial as
it’s stated on nih.gov had to say. More than 37 million, that’s 37 million, people
are living with HIV. And, get this, every single day it is spread to approximately
5,000 new people. Which amounts to approximately 1.8 million new
transmissions of HIV every year. And of those 1.8 million 10 percent, that’s a
hundred and eighty thousand, are newborns. So it’s being transmitted from parent to
child. In the United States men who have sex
with men account for nearly two-thirds of new HIV infections that’s a lot and
the nearly 25 million transgender people around the world approximately 50 times
more at risk of getting HIV than the general population now in eastern and
southern Africa women and girls are 60% of people living with HIV that’s 6-0 60
% HIV does not discriminate it is not just a virus that affects the LGBT
community as you can tell by those living in eastern and southern Africa
it affects large swathes of people and it is something that we are fighting to
tackle every day here in the US and around the world and so this new vaccine
potential vaccine that’s going into clinical trials
is yet another avenue from which we can poke back and say not today HIV a little
bit of tidbits about HIV HIV has more genetic diversity than any other known
virus why because as HIV replicates itself it’s not very good at it
so it ends up having a lot of mistakes in its genetic coding which are known as
mutations so the virus mutates a lot on accident and regardless of it mutating
so much it’s able to survive with the new mutations so every time that happens
you’re essentially creating a potentially new strain of the virus that
is going to function in a slightly different way so if you’re creating a
vaccine that only targets one strain that’s not enough that’s not going to
cut it because the virus is constantly mutating and creating new strains and we
need a vaccine that’s going to be able to tackle multiple large strains of the
virus to really have any practical large-scale use Johnson & Johnson is
conducting the large-scale clinical trial and the trial is called Mosaico
so it’s like mosaic but with an O at the end their potential vaccine is designed
to be effective against multiple strains of HIV and that’s exactly what we want
the scientists plan to enroll 38(hundred) healthy participants at 50 trial sites located
north and South America and in Europe so in North America it’s going to be the US
as well as Mexico South America we’ve got Argentina Brazil Peru and then in
Europe Italy Poland and Spain so that’s what I was able to see on the NIH
website as far as where they’re gonna have clinical trial sites if you’re
interested it’s going to be in the fall so you might want to look that up if you
want to be a part of that study the study will be a double-blind meaning
that some of the participants will receive the experimental vaccine while
others will receive a placebo and a placebo is basically nothing it’s could
be saline water and that’s just to ensure that the medicine is actually
what is causing the effects in the participant and not the placebo effect
of people thinking that they’re receiving
treatment and that somehow having an effect on the virus in their body
double-blind got participants with the experimental vaccine some placebo and
also neither the participants nor the researchers will know who is getting
what until the end now I want to reiterate again this is not the only
clinical trial that’s going on for an experimental vaccine there’s for example
one in sub-saharan Africa a similar vaccine is being tested on 2,600 women
who in that region are the most at-risk population for HIV transmission that
trial began 2017 and the results from that won’t be available till minimum
2021 there are also other trials going on in North and South America as well as
Africa I want to quote from the LA Times article that researchers with the
International AIDS vaccine initiative determined that a vaccine that 70%
effective would do more to prevent new infections than PrEP so PrEP is a pill
that you can take once a day take it every day
and it prevents HIV transmission by I think 96 to 96 to 99 percent which is
amazing it’s a huge you know jump that we’ve made to be able to do that to
offer that to people what they’re saying is that if this vaccine is 70% effective
it will do more to prevent new HIV transmissions then prep now the Mosaico
trial is pushing for 65 percent effectiveness that is their specific
goal being able to have a vaccine would be an amazing advancement towards ending
the HIV epidemic even at 65 percent efficacy that combined with prep in
conjunction with the state for sex practices like using condoms also you
equals you or undetectable equals on transmittable for those of us living
with HIV when you are on effective treatment and the virus is suppressed in
the blood and considered undetectable for six months or more then you can no
longer sexually transmitted the virus in are considered untransmittable so all
these things combined with education and stigma reduction access to health care
are going to have an incredible impact on our ability to combat HIV
transmissions and the epidemic as we are continuing to work towards
a functional and practical cure for the general population so that’s my little
tidbit I want to share with you guys just another reason for us to continue
to have hope and continue to go about living our lives knowing that HIV is not
going to be something that has to restrict limit or be a source of stigma
or hold us back for anything really so I will keep you guys updated happy new
year I hope this great news finds you well
and I will be in touch soon let me know what you guys think as always like this
video if you liked it comment below subscribe if you haven’t already and
I’ll see you guys soon peace. Say bey buddy. Come here Say goodbye. Say goodbye. Bye. Good boy